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. 2022 Jun 15;20(6):396. doi: 10.3390/md20060396

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic illustration for the formation of dendronized chitosan (DC) hydrogels and the application for corneal stromal defects. (A) Cartoon presentation of DCs featured with radial amphiphilicity and their self-assembly in water to form fibrous bundles and the instant formation of hydrogels via heating around physiological temperature. (B) Injection of DC solution into the corneal stromal defects of a rabbit model, in situ formation of a hydrogel filler, and defects repairing. Reprinted with permission from Feng et al. [152]. Copyright 2021, American Chemical Society.