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Gypenoside XVII inhibits C3aR-STAT3 cytokines signaling in the prefrontal cortex (n = 4–6). C3aR levels were detected by both immunofluorescence (A,B) and Western blot (C). pSTAT3/STAT3 was detected by Western blot (D). The mRNA expression of IL-1β (E), IL-6 (F) and TNF-α (G) was detected by PCR. # p < 0.05 and ## p < 0.01 versus the Normal-vehicle group. * p < 0.05 and ** p < 0.01 versus the CUMS-vehicle group.
