Table 2.
Intra-day and inter-day accuracy and precision of MPI8 in rat plasma.
| Nominal Concentration (ng/mL) | Intra-Day (n = 6) | Inter-Day (n = 18) | ||||
|---|---|---|---|---|---|---|
| Observed Concentration (Mean ± SD) |
Accuracy (RE%) |
Precision (CV%) |
Observed Concentration (Mean ± SD) |
Accuracy (RE%) |
Precision (CV%) |
|
| 0.5 (LLOQ) | 0.44 ± 0.04 | −12.03 | 10.10 | 0.46 ± 0.06 | −8.44 | 12.03 |
| 1.5 (LQC) | 1.48 ± 0.15 | −1.44 | 9.92 | 1.51 ± 0.16 | 0.93 | 10.53 |
| 25 (MQC) | 26.88 ± 2.07 | 7.53 | 7.69 | 25.54 ± 3.07 | 2.16 | 12.01 |
| 400 (HQC) | 378.17 ± 28.05 | −5.46 | 7.42 | 393.61 ± 52.43 | −1.60 | 13.32 |