Skip to main content
. 2022 Jun 9;27(12):3716. doi: 10.3390/molecules27123716

Scheme 53.

Scheme 53

Synthesis of 1,2,3-triazolyisoindoline-1,3-dione derivatives 119af. Reagents and conditions: (a) Acetic acid, 100 °C, 3 h; (b) K2CO3, Propargyl bromide, DMF, room temperature, 3 h; (c) Azides, 10 mol% of sodium ascorbate, 10 mol% of CuSO4·H2O, DMF: Water (1:1), room temperature, 10 to 12 h.