Table 3.
Features, molecular typing, resistance profile, plasmid replicon types, and virulence-associated factors of ST383 K. pneumoniae K22 strain isolated from Egypt.
| ST a | CPS b | LPS c |
wzc- allele d |
wzi- typing e |
Resistance Profile f | Plasmid Replicon Type g | Virulence h | ||
|---|---|---|---|---|---|---|---|---|---|
| Antimicrobial Class | Antimicrobial Resistance Genes |
Virulence Determinants |
Heavy Metal Resistance |
||||||
| ST383 | K51 | O1 | wzc-50 | wzi-705 | Phenicols | catA1, catB3 | Col(KPHS6) ColRNAI Col440II IncFIBK IncFIB IncHI1B IncFIIK IncL/M |
irp1
fyuA ybtAEPQSTUX iutA iucABCD rmpA, rmpA2 rmpC mrkABDFHIJ |
terABCDEWXYZ
arsABCDR pcoABCDRSE silABCEFGPRS |
| Sulphonamides | sul1, sul2 | ||||||||
| Fosfomycin | fosA | ||||||||
| Trimethoprim | dfrA5 | ||||||||
| β-Lactams |
blaSHV-26, blaTEM-1, blaNDM-5, blaOXA-1, blaOXA-9, blaOXA-48, blaCTX-M-14b, blaCTX-M-15 |
||||||||
| Aminoglycosides | aph(6)-Id, aph(3″)-Ib, aph(3′)-VIb, aadA1, aph(3′)-VI, aac(6′)-Ib, armA | ||||||||
| Macrolides, lincosamides and streptogramin B |
mphE, msrE, mphA | ||||||||
| Fluoroquinolones | aac(6′)-Ib-cr, qnrS1, oqxA, oqxB | ||||||||
| Tetracycline | tetA | ||||||||
a ST, sequence type, data obtained from MLST v 2.0; b CPS, capsular polysaccharide, K-typing determined by K-PAM in silico diagnostic tool; c LPS, lipopolysaccharides, O-typing determined by K-PAM in silico diagnostic tool; d typing of wzc as determined from Institut Pasteur database; e wzi typing as determined from Institut Pasteur database; f antimicrobial resistance genes as obtained from ResFinder v 4.1, CGE pipelines; g data represent plasmid incompatibility (Inc) group designations as determined by PlasmidFinder v 2.1, CGE pipelines; h data obtained from Institut Pasteur database.