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Composition and molar ratio of various liposomal formulations.
| Ingredients | F1 | F2 * | F3 # |
|---|---|---|---|
| DOPE | 40 | - | 40 |
| CHEMS | 30 | 30 | |
| DSPE-mPEG (2000) | 5 | - | 5 |
| DSPC | - | 10 | - |
| Cholesterol | - | 5 | - |
| CL | 17 | - | 17 |
| SA | 8 | - | 8 |
| DNR:lipid ratio | 1:5 | 1:10:5 | - |
* Liposomal formulation similar to DaunoXome®. 1:10:5 is the molar ratio of daunorubicin:DSPC:cholesterol. 1:5 is the molar ratio of daunorubicin:total lipids. # Blank formulation, used in the cytotoxicity studies.
