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Histological analysis, MPO level, and pro-inflammatory mRNA levels of M13/nLNP-modified microbial metabolites during the UC progression of IL-10 KO mice. (A) H&E staining (white arrows indicate inflammatory cells in the lamina propria); (B) colonic MPO level; (C) measurement of mRNA levels of cytokines. (n = 4; *** p < 0.001, ** p < 0.01, * p < 0.05, NS—non-significant).
