Table 5.
Hazard ratios (HR) for omega-3 index on Alzheimer’s disease (AD) and all-cause dementia (n = 1490).
| Endpoint | HR (95% CI) for Quintiles of Omega-3 Index | HR (95% CI) per SD 1 | |||||
|---|---|---|---|---|---|---|---|
| Q1 (<4.3%, Median = 3.9%) (n = 300) |
Q2 (4.3% to <5.1%, Median = 4.7%) (n = 300) |
Q3 (5.1% to <5.9%, Median = 5.4%) (n = 298) |
Q4 (5.9% to 7.1%, Median = 6.3%) (n = 293) |
Q5 (>7.1%, Median = 8.0%)(n = 299) |
p for Trend | ||
| AD | |||||||
| N. of cases | 29 | 31 | 24 | 27 | 20 | 131 | |
| Model 1 | 1.00 | 0.81 (0.49, 1.36) | 0.60 (0.34, 1.08) | 0.74 (0.43, 1.29) | 0.52 (0.28, 0.93) | 0.04 | 0.83 (0.67, 1.02) |
| Model 2 | 1.00 | 0.90 (0.52, 1.54) | 0.62 (0.34, 1.15) | 0.81 (0.45, 1.45) | 0.55 (0.29, 1.05) | 0.08 | 0.85 (0.68, 1.05) |
| Model 3 | 1.00 | 0.90 (0.52, 1.54) | 0.61 (0.33, 1.14) | 0.81 (0.45, 1.45) | 0.55 (0.29, 1.03) | 0.07 | 0.84 (0.68, 1.04) |
| Dementia | |||||||
| N. of cases | 34 | 39 | 32 | 36 | 27 | 168 | |
| Model 1 | 1.00 | 0.90 (0.56, 1.44) | 0.72 (0.43, 1.22) | 0.88 (0.54, 1.44) | 0.61 (0.36, 1.03) | 0.09 | 0.87 (0.73, 1.04) |
| Model 2 | 1.00 | 0.93 (0.57, 1.50) | 0.73 (0.42, 1.25) | 0.93 (0.56, 1.54) | 0.63 (0.36, 1.09) | 0.14 | 0.88 (0.74, 1.05) |
| Model 3 | 1.00 | 0.93 (0.57, 1.51) | 0.72 (0.42, 1.24) | 0.92 (0.56, 1.53) | 0.62 (0.36, 1.07) | 0.12 | 0.88 (0.73, 1.05) |
1 1 SD = 1.70% of total fatty acids. CI = confidence interval; Q = quintile; SD = standard deviation. See Table 2 for detailed information on statistical models.