Table 1.

Demographics and body weight normalized dose in the pediatric population with heart failure due to dilated cardiomyopathy and congestive heart failure.

Patient Group	n	Gender (m)	Age (Years)	Body Weight (kg)	Dose (mg/kg)	Height (cm)	GFR * (mL/min)	BSA * (m2)
Total (ALL)	89	49 (55%)	0.422 (0.064–11.0)	5.93 (2.52–49.1)	0.0718 (0.0167–0.290)	65 (49.8–168.4)	118.8 (49.6–233.1)	0.327 (0.184–1.42)
1 day to <1 year	66	38 (58%)	0.363 (0.064–0.997)	4.93 (2.52–9.2)	0.06906 (0.0347–0.133)	61 (49.8–77.7)	115.8 (49.6–233.1)	0.285 (0.187–0.441)
1 year to <6 years	17	10 (59%)	1.75 (1.036–5.25)	11.9 (6.87–21)	0.09617 (0.0167–0.148)	85.6 (67.6–115.9)	125 (78.4–168.5	0.532 (0.370–0.795)
6 years to <12 years	6	4 (67%)	10.5 (6–11.02)	32.3 (17.8–49.1)	0.15658 (0.0396–0.290)	142.1 (111.9–168.4)	109.95 (94.2–151.1)	1.11 (0.74–1.41)
Dilated Cardiomyopathy	26	17 (65%)	1.54 0.296–11.02	9.83 5.48–49.1	0.107 0.027–0.290	81.5 62–168.4	112.7 71.8–151.1	0.463 0.311–1.41
1 months to <1 year	9	6 (67%)	0.844 (0.296–0.997)	8.9 (5.48–9.2)	0.107 (0.04–0.133)	73.5 (62–76.5)	100 (71.8–171.5)	0.429 (0.311–0.441)
1 year to <6 years	11	7 (64%)	1.75 (1.25–5.25)	10.3 (6.87–19.6)	0.1 (0.027–0.143)	84.4 (74.0–115.9)	114.5 (78.4–148.6)	0.491 (0.386–0.795)
6 years to <12 years	6	4 (67%)	10.5 (6–11.0)	32.3 (17.8–49.1)	0.157 (0.0396–0.290)	142.1 (111.9–168.4)	109.95 (94.2–151.1)	1.11 (0.74–1.41)
Congenital Heart Disease	63	32 (51%)	0.362 0.064–5	4.84 2.52–21.06	0.068 0.017–0.148	61.0 49.8–115	125.7 49.6–233.1	0.284 0.187–0.768
1 day to <1 year	56	29 (52%)	0.322 (0.064–0.751)	4.535 (2.52–8.78)	0.0651 (0.0347–0.133)	58.6 (49.8–77.7)	122.2 (49.6–233.1)	0.273 (0.187–0.435)
1 year to <6 years	7	3 (43%)	3.67 (1.04–5)	13.6 (7.3–21.0)	0.08 (0.017–0.148)	96.7 (67.5–115)	156.3 (108.2–168.5)	0.606 (0.370–0.768)

* GFR = Glomerular Filtration Rate; BSA = Body Surface Area.