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Individual age, body weight and pharmacokinetic parameters of the four male neonates with congenital heart defects below 28 days of age.
| Age | Body Weight | Enalapril | Enalaprilat | Enalapril | Enalaprilat | Enalapril | Enalaprilat |
|---|---|---|---|---|---|---|---|
| (days) | (kg) | AUCtau, ss, norm (ng/mL·h/mg·kg) |
Cmax, ss, norm (ng/mL/mg·kg) |
tmax or tmax, ss (h) |
|||
| 17 | 4.35 | 775.3 | 259.5 | 1344.6 | 174.9 | 2.05 | 5.983 |
| 24 | 3.28 | 996 | 274.8 | 504.9 | 101.8 | 3.983 | 11.9 |
| 25 | 3.50 | 318.6 | 103.8 | 1111.7 | 152.5 | 1 | 5.983 |
