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. 2022 Jun 15;14(6):1270. doi: 10.3390/pharmaceutics14061270

Figure 1.

Figure 1

Schematic representation of the incidence of A673T mutation by country using BioRender. In the Icelandic population, the frequency of the A673T mutation was reported to be 0.13% in AD cases and up to about 0.70% in controls. In other large-scale studies, frequencies were reported to be 0.51% for Finnish subjects with AD, 0.42% for Swedish, 0.21% for Norwegian, 0.014% Danish and 0.011% for American; and 0.018% for cognitively normal controls. The A673T mutation appeared to be absent in a screen of 8721 Asian individuals, and in 2641 healthy longevity Chinese subjects. AD, Alzheimer’s disease; USA, United States of America.