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. 2022 Jun 15;14(6):1270. doi: 10.3390/pharmaceutics14061270

Figure 3.

Figure 3

Schematic representation of the involvement of the Icelandic mutation in Alzheimer’s disease regarding genome editing tools. The figure was prepared with BioRender. APP, amyloid precursor protein; Aβ, amyloid-beta peptide; PSEN1, presenilin 1; PSEN2, presenilin 2; APOE, apolipoprotein E.