Table 4.
Unadjusted comparison of post-faecal microbiota transplantation [FMT] variables among paediatric subjects with inflammatory bowel disease [IBD].
| Group [reduction in sample size show in parentheses] | No Response [n = 36] | Response [n = 112] | OR [95% CI] | p* |
|---|---|---|---|---|
| Hospitalisation related to IBD within 3 months post-FMT | 7 [19%] | 12 [11%] | 0.49 [0.18 – 1.35] | 0.17 |
| IBD-related surgery within 3 months post-FMT | 1 [3%] | 8 [7%] | 1.92 [0.30 – 12.47] | 0.49 |
| New medication within 3 months post-FMT | 14 [39%] | 43 [38%] | 0.97 [0.45 – 2.09] | 0.94 |
| Clinically active IBD within 3 months post-FMT | 31 [86%] | 61 [54%] | 0.21 [0.08 – 0.56] | 0.002 |
| IBD clinical response 3 months post-FMT [no response n = 32, response n = 103] | 0.07 | |||
| Improved | 7 [22%] | 44 [43%] | 1.79 [0.55 – 5.88] | |
| No change | 19 [59%] | 38 [37%] | 0.60 [0.21 – 1.70] | |
| Worsened | 6 [19%] | 21 [20%] | Reference |
OR, odds ratio; CI, confidence interval.
a p-value from unadjusted logistic regression.