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Multiple sequence alignment of the receptor-binding domains amino acid sequences of five SARS-CoV-2 variants. Contacting residues in the SARS-CoV-2 receptor-binding domain are indicated by an asterisk. The receptor-binding motif sequence is shown in red. The surface glycoprotein receptor-binding domain sequences are from GenBank, with the following accession protein ID: UFZ12739.1 (Alpha), QWW93436.1 (Beta), QWW27582.1 (Gamma), UAL04647.1 (Delta), and UKO09871.1 (Omicron).
