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. 2022 Jun 16;14(6):1283. doi: 10.3390/pharmaceutics14061283

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© 2022 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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CSF flow and volume in humans and animals. (Left) CSF, shown in blue or brown, is produced at the choroid plexus lining the ventricles (red) and flows around the surface of the brain or spinal cord, and is absorbed into the venous blood of the superior sagittal sinus at the arachnoid villi. The septum pellucidum separates the 2 lateral ventricles into separate compartments. The cisterna magna is at the base of the cerebellum next to the brain stem. Reproduced with permission from [984], Copyright© 2016, Elsevier. (Right) The brain weights, total CSF volume, and lateral ventricle (LV) volumes for humans, monkeys, rats, and mice are shown. CSF volumes are from [985], and the LV volumes are from [74], for the rat, from [986], for the mouse, from [987], for the monkey, and from [988], for humans.