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. 2022 Jun 16;14(6):1283. doi: 10.3390/pharmaceutics14061283

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© 2022 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Astrocyte endfeet and brain extracellular space in cryo-fixed and chemical-fixed brain. (A,B) Brain capillary ultrastructure after cryo-fixation (A) and chemical fixation (B). The astrocyte endfeet are pseudo-colored in orange. An erythrocyte is present within the capillary lumen in (A). (C,D). Brain extracellular space after cryo-fixation (C) and chemical fixation (D). The extracellular space is pseudo-colored in blue. Reproduced from [22], Copyright© 2015 licensed under Creative Commons Attribution License (CC-BY).