Table 1.
Brain drug delivery citations in PubMed.
| No. | Delivery Technology Keyword a | Citations | No. | Delivery Technology Keyword a | Citations |
|---|---|---|---|---|---|
| 1 | Nanoparticles (1995) | 4169 | 11 | Cationic (1987) | 437 |
| 2 | Ultrasound (2001) | 1472 | 12 | p-glycoprotein (1989) | 382 |
| 3 | Cerebral implant (1994) | 1417 | 13 | Transferrin receptor (1991) | 373 |
| 4 | Liposomes (1990) | 1285 | 14 | Dendrimers (2004) | 364 |
| 5 | Nasal (1982) | 1024 | 15 | Carrier-mediated transport (1975) | 327 |
| 6 | Lipid carrier (1996) | 814 | 16 | Cell-penetrating peptide (2000) | 263 |
| 7 | Cerebrospinal fluid (1963) | 666 | 17 | Exosomes (2011) | 224 |
| 8 | BBB disruption (1979) | 627 | 18 | Tat (1994) | 155 |
| 9 | Small molecules (1954) | 598 | 19 | Insulin receptor (1995) | 134 |
| 10 | Receptor-mediated transport (1986) | 566 | 20 | Convection-enhanced diffusion (1994) | 124 |
a PubMed search term is ‘brain drug delivery and keyword’, and each of the 20 keywords is listed in Table. The first year of publication of the brain drug delivery technology is given in parenthesis next to the technology keyword.