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. 2022 Jun 16;14(6):1283. doi: 10.3390/pharmaceutics14061283

Table 3.

Vitamin transporters at the blood–brain barrier.

Vitamin MW Polarity Transporter SLC
Thiamine (B1) 265 charged THTR2 19A3
Riboflavin (B2) 376 hydrophilic RFVT2 52A2
Niacin (B3) 123 carboxylate MCT1 16A1
Pantothenic acid (B5) 219 carboxylate SMVT 5A6
Pyridoxine (B6) 169 hydrophobic THTR2 19A3
Biotin (B7, B8) 244 carboxylate SMVT 5A6
Folic acid (B9, B11) 441 hydrophilic FOLR1 receptor
Cobalamin (B12) 1355 hydrophilic TCBLR receptor