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. 2022 Jun 11;27(12):3761. doi: 10.3390/molecules27123761

Scheme 2.

Scheme 2

Reagents and conditions: (a) (R)- or (S)-2-aminopropanol or cis-4-hydroxy-l-proline methyl ester hydrochloride, MeCN, rt, overnight; (b) NaN3, EtOH, reflux, 18 h.