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IFNα/β generates the antiviral response to control ZIKV infection. IFNα: Interferon alpha; IFNβ: Interferon beta; IFNAR1: interferon alpha receptor 1; IFNAR2: interferon alpha receptor 2; TYK2: Tyrosine kinase 2; JAK1: Janus activated kinase 1; STAT1: signal transducer and activator of transcription 1; STAT2: signal transducer and activator of transcription 2; IRF9: interferon regulatory factor 9; ISG: Interferon-stimulated genes.
