Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 24;10:96. doi: 10.1186/s40168-022-01264-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 6 — Metaproteomics of intestinal microbiota. a Principal component analysis (PCA) of protein group abundances reveals significant differences (PERMANOVA P = 0.001) in the metaproteomes between treatments. b Significant changes (Kruskal-Wallis test P = 0.0456) in the abundance of choloylglycine hydrolase function (KEGG K01442), known to deconjugate conjugated bile acids, between treatments in the intestinal microbiome was observed, with the post hoc pairwise analysis revealing a significant change between RYGB and DIO (Dunn test, P = 0.0069 (**)), and a trend between DIO and FMT^RYGB (Dunn test, P = 0.0823 (#)). c Microbiome bacteria genera that are significantly associated with the abundance of choloylglycine hydrolase. n = 6–10 animals per group with pooled data from 3 independent experiments