Table 3.
Resistance to anti-TB drugs (%) among strains isolated from patients with multidrug-resistant osteoarticular TB in France (n = 23) and among all strains isolated from MDR-TB patients (n = 863), from 2007 to 2018.
| Drug | MDR-OATB 1 n (%) |
MDR-TB n (%) |
p-Value |
|---|---|---|---|
| Rifampin | 18 (78) high level/5 (22) low level 2 | 837 (97) high level/26 (3) low level | <0.01 |
| Protionamide | 15 (65) | 673 (78) | 0.06 |
| Streptomycin | 15 (65) | 811 (94) | <0.01 |
| Ethambutol | 12 (52) | 681 (79) | <0.01 |
| Pyrazinamide | 6 (26) | 379 (44) | 0.01 |
| Kanamycin | 3 (13) | 267 (31) | <0.01 |
| Cycloserine | 2 (9) | 215 (25) | <0.01 |
| Amikacin | 2 (9) | 121 (14) | 0.38 |
| Ofloxacin | 2 (9) | 259 (30) | <0.01 |
| Moxifloxacin | 2 (9) | 259 (30) | <0.01 |
| Bedaquiline 3 | 1 (4) | 34 (4) | 1 |
| Capreomycin | 1 (4) | 138 (16) | <0.01 |
| PAS | 1 (4) | 155 (18) | <0.01 |
| Linezolid | 0 (0) | 0 (0) | 1 |