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. 2022 May 24;14(6):1118. doi: 10.3390/pharmaceutics14061118

Table 4.

Ex vivo pharmacokinetic parameters of 89Zr-Exo following i.v. administration in various organs of SD rats.

Organ Cmax [%ID] Tmax [d] AUC0-t [%ID × d]
Liver 38.13 2.00 256.82
Spleen 3.19 0.25 18.73
Brain 0.02 2.00 0.11
Small intestine 6.77 0.08 2.22
Large intestine 7.91 0.25 6.04
Stomach 0.55 0.01 0.46
Kidney 2.79 7.00 17.37
Urine * 17.33 0.01 1.46
Lung 4.45 0.01 2.57
Heart 0.06 0.01 0.19
Thyroid 0.01 0.01 0.07
Testis 0.06 0.01 0.25
Ovary 0.02 0.01 0.09
Muscle * 0.03 0.01 0.06
Femur * 0.31 7.00 1.70
Blood * 0.12 0.01 0.09

* Unit (concentration) = %ID/g.