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. 2022 Jun 3;10(6):894. doi: 10.3390/vaccines10060894

Table 1.

Immunization plan followed in the experimental birds.

Groups (n=10 or 11/Group) * Vaccine (Dose/Bird) TLR Agonist(s) (Dose/Bird)
Control (A) PBS -
Commercial vaccine (B) Commercial oil adjuvanted inactivated NDV vaccine (recommended dose) -
Vaccine alone (C) Inactivated NDV vaccine (≥107 EID50) -
Vaccine + TLR4 agonist (D) Inactivated NDV vaccine (≥107 EID50) LPS (50 µg)
Vaccine + TLR7 agonist (E) Inactivated NDV vaccine (≥107 EID50) R-848 (50 µg)
Vaccine + TLR4 and TLR7 agonists in
low dose (F)		 Inactivated NDV vaccine (≥107 EID50) LPS (25 µg) +
R-848 (25 µg)
Vaccine + TLR4 and TLR7 agonists in high dose (G) Inactivated NDV vaccine (≥107 EID50) LPS (50 µg) +
R-848 (50 µg)

* The number of birds was 10 in each group except groups F and G, where it was 11/group. +, indicate usage in combination.