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. 2022 Jun 24;22:819. doi: 10.1186/s12913-022-08187-9

Table 3.

Analyses using self-reported CHU9D and tariffs from an adult population

Self-reported CHU9D
Tariffs based on preferences of a youth population
Parent-reported CHU9D
Tariffs based on preferences of an adult population
MMM (n = 197)
mean ± se
MAU (n = 199)
mean ± se
MMM (n = 197)
mean ± se
MAU (n = 199)
mean ± se
Baseline 0.642 ± 0.016 0.631 ± 0.016 0.806 ± 0.009 0.802 ± 0.008
End-of-treatment (week 18) 0.728 ± 0.016 0.684 ± 0.018 0.873 ± 0.008 0.844 ± 0.009
Follow-up (week 26) 0.769 ± 0.015 0.708 ± 0.186 0.886 ± 0.008 0.839 ± 0.009
QALY 0.352 ± 0.007 0.335 ± 0.007 0.426 ± 0.003 0.414 ± 0.004
Incremental QALYs
 Unadjusted 0.017 ± 0.009 0.012 ± 0.005
 Adjusted for baseline 0.014 (95% CI: 0.002–0.027) 0.010 (95% CI: 0.004–0.016)
 ICER €210,757 /QALY gained €291,916 /QALY gained

Values presented are the mean (standard error (SE)) of the intention-to-treat population from 20 imputed datasets. Adjusted incremental quality adjusted life years (QALY) are adjusted for baseline utility. The confidence intervals (CIs) were derived from 10,000 bootstrap replications from 20 imputed datasets using the standard normal method

CHU9D Child Health Utility 9D, ICER Incremental Cost-Effectiveness Ratio