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. 2022 Jun 9;15(6):732. doi: 10.3390/ph15060732

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Isobolograms for the interaction of PX (A,C,E) and PCX (B,D,F) with SN-38 in HCT-116 (A,B), Caco-2 (C,D), and HT-29 cells (E,F). The isobolograms were constructed by connecting the IC₃₀ (triangles), IC₅₀ (circles), and IC₇₀ (squares) values of pectins with the appropriate IC values of SN-38. Lines indicate the theoretical lines of additivity.