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. 2022 Jun 9;15(6):732. doi: 10.3390/ph15060732

Figure 3.

Figure 3

Synergism of apple pectins PX (A,C,E) and PCX (B,D,F) with anticancer drug SN-38 in colon cancer cells HCT 116 (A,B), Caco-2 (C,D), and HT-29 (E,F). The matrices show Combenefit analysis of the combinations. MTT cell viability data after 48 h of incubation (arithmetically averaged data of three independent experiments) were used for the analysis. Synergy score: less than −5—the interaction between two drugs is likely to be antagonistic; from −5 to 5—the interaction is likely to be additive; larger than 5—the interaction is likely to be synergistic.