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Detection of intercalating compounds 1–4 in the LLAMAS (DNA-binding) assay. The UV chromatograms (λ 254 nm) show the peak areas of the filtrate for the control group samples incubated without DNA compared to experimental group samples that were incubated with DNA (overlying traces, upper panels). The compounds bound to the DNA were subsequently dissociated with MeOH containing 0.1% formic acid (lower panels) (NL: normalized intensity).
