Table 1.
Characteristics of colorectal cancer patients by C-reactive protein (CRP) quintiles
| Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | ||
|---|---|---|---|---|---|---|
| N | 248 | 245 | 249 | 247 | 246 | |
| CRP Quintile ranges, mg/L | 0.20–0.73 | 0.74–1.81 | 1.82–3.31 | 3.32–5.57 | ≥ 5.58 | |
| CRP, mg/L, median (Q25, Q75) | 0.34 (0.20, 0.47) | 1.19 (0.95, 1.45) | 2.53 (2.16, 2.87) | 4.21 (3.65, 4.87) | 8.86 ( 6.82–13.02) | |
| Female sex, n (%) | 131 (52.8) | 111 (45.3) | 113 (45.4) | 133 (53.8) | 138 (56.1) | |
| Age at diagnosis, years, mean (SD) | 61.0 (7.4) | 62.3 (7.4) | 62.4 (7.1) | 63.3 (7.0) | 63.1 (7.3) | |
| Current smoking, n (%) | 74 (29.8) | 52 (21.2) | 61 (24.5) | 67 (27.1) | 58 (23.6) | |
| Physical activity (MET-hours/week), mean (SD) | 83.6 (52.7) | 85.7 (55.5) | 81.7 (50.1) | 85.2 (51.7) | 86.5 (54.9) | |
| Body mass index, kg/m2, mean (SD) | 24.5 (3.4) | 26.0 (3.6) | 26.7 (3.8) | 27.4 (4.1) | 28.9 (5.3) | |
| Waist circumference, cm, mean (SD) | 84.1 (11.9) | 88.9 (12.6) | 90.8 (11.9) | 92.3 (12.5) | 95.9 (13.8) | |
| Diabetes, n (%) | 12 ( 5.0) | 14 ( 5.9) | 17 ( 6.9) | 36 (14.7) | 44 (18.6) | |
| Family history of CRC, n (%) | 6 ( 9.7) | 4 ( 6.7) | 4 ( 7.1) | 6 ( 8.8) | 7 (10.3) | |
| Location of primary tumor, n (%) | ||||||
| Colon | 152 (61.3) | 139 (56.7) | 148 (59.4) | 160 (64.8) | 181 (73.6) | |
| Rectum | 96 (38.7) | 106 (43.3) | 101 (40.6) | 87 (35.2) | 65 (26.4) | |
| Grade of differentiation, n (%) | ||||||
| Well differentiated | 16 (6.5) | 11 (4.5) | 15 (6.0) | 15 (6.1) | 14 (5.7) | |
| Moderately differentiated | 66 (26.6) | 65 (26.5) | 73 (29.3) | 81 (32.8) | 74 (30.1) | |
| Poorly differentiated | 14 (5.6) | 21 (8.6) | 17 (6.8) | 9 (3.6) | 20 (8.1) | |
| Unknown | 152 (61.3) | 148 (60.4) | 144 (57.8) | 142 (57.5) | 138 (56.1) | |
| Stage, n (%) | ||||||
| I | 73 (29.4) | 66 (26.9) | 64 (25.7) | 46 (18.6) | 58 (23.6) | |
| II | 58 (23.4) | 41 (16.7) | 51 (20.5) | 54 (21.9) | 53 (21.5) | |
| III | 56 (22.6) | 79 (32.2) | 69 (27.7) | 85 (34.4) | 81 (32.9) | |
| IV | 25 (10.1) | 20 (8.2) | 34 (13.7) | 34 (13.8) | 32 (13.0) | |
| Unknown | 36 (14.5) | 39 (15.9) | 31 (12.4) | 28 (11.3) | 22 (8.9) | |