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. 2022 Jun 10;10(6):315. doi: 10.3390/toxics10060315

Table 2.

Associations between TCDD and TEQ-PCDD/Fs concentration and biomarker indices.

TCDD TEQ-PCDD/FS
Markers N β 95% CI
(Lower, Upper)
p β 95% CI
(Lower, Upper)
p
Aspartate Aminotransferase (AST) 33 0.414 (0.071, 0.758) 0.020 0.393 (0.046, 0.741) 0.028
Alanine Aminotransferase (ALT) 33 0.359 (0.009, 0.709) 0.045 0.349 (−0.003, 0.702) 0.052
Gamma-Glutamyl Transpeptidase (GGT) 33 0.340 (−0.020, 0.699) 0.063 0.298 (−0.068, 0.664) 0.107
Total Bilirubin 33 0.389 (0.030, 0.748) 0.035 0.283 (−0.091, 0.656) 0.133
Glucose 33 −0.05 (−0.417, 0.318) 0.79 −0.14 (−0.502, 0.229) 0.45
Urea 33 0.031 (−0.318, 0.381) 0.855 −0.013 (−0.364, 0.337) 0.938
Creatinin 33 −0.011 (−0.284, 0.262) 0.933 0.062 (−0.211, 0.334) 0.648
Protein 33 0.421 (0.104, 0.738) 0.011 0.351 (0.021, 0.680) 0.038
Cholesterone 33 0.029 (−0.334, 0.392) 0.871 0.006 (−0.358, 0.370) 0.974
Triglyceride 33 0.043 (−0.334, 0.420) 0.816 0.104 (−0.272, 0.480) 0.576
Red Blood Cells 33 0.137 (−0.200, 0.474) 0.412 0.078 (−0.263, 0.418) 0.644
Hemoglobin 33 0.003 (−0.288, 0.294) 0.985 −0.024 (−0.316, 0.267) 0.866
Leukocytes 33 −0.031 (−0.420, 0.357) 0.870 −0.225 (−0.605, 0.155) 0.236
Neutrocytes 33 −0.201 (−0.582, 0.181) 0.291 −0.240 (−0.619, 0.139) 0.205
Lymphocytes 33 0.234 (−0.146, 0.614) 0.218 0.299 (−0.075, 0.673) 0.113
Platelets 33 −0.172 (−0.549, 0.206) 0.360 −0.127 (−0.508, 0.254) 0.500

TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; PCDD/Fs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo furans; TEQ, toxic equivalent quantity; N, number of subjects; β, standardized beta; 95% CI, 95% confidence interval. Confounding factors: gender; age; smoking status.