Table 1.
The basal characteristics of obese normoglycemic (NG) and T2D women.
| Parameters | NG Women n = 65 | T2D Women n = 63 | p |
|---|---|---|---|
| Age (years) | 50.0 ± 5.0 | 53.2 ± 5.0 | <0.001 |
| BMI (kg/m2) | 36.5 ± 6.2 | 36.6 ± 6.3 | 0.91 |
| WC (cm) | 106.8 ± 16.4 | 107.7 ± 13.9 | 0.76 |
| Glucose (mmol/L) | 5.2 (4.8–5.4) | 7.0 (5.9–8.1) | <0.0001 |
| HDL-C (mmol/L) | 1.4 (1.2–1.7) | 1.2 (1.0–1.4) | 0.001 |
| TG (mmol/L) | 1.3 (0.9–1.6) | 1.7 (1.3–2.2) | 0.0001 |
| ALT (U/L) | 18.7 (14.2–23.8) | 22.7 (17.8–30.4) | 0.009 |
| GGT (U/L) | 20.7 (14.6–25.8) | 25.2 (18.9–33.7) | 0.011 |
| Creatinine (mg/dl) | 0.76 (0.72–0.88) | 0.81 (0.73–0.89) | 0.23 |
| eGFR (mL/min/1.73 m2) | 91.9 (80.2–96.4) | 83.1 (71.7–92.4) | 0.04 |
| CRP (mg/L) | 2.3 (1.0–3.9) | 3.3 (1.3–5.9) | 0.08 |
| HbA1c (mmol/mol) | 37.0 (34.0–38.0) | 45.0 (42.0–58.0) | <0.0001 |
| Insulin (µIU/mL) | 9.0 (6.7–12.1) | 10.5 (5.8–15.0) | 0.29 |
| TSH (mIU/L) | 1.48 (1.14–2.10) | 1.34 (1.01–2.05) | 0.31 |
| HOMA-IR | 2.0 (1.6–2.9) | 3.3 (1.9–5.5) | 0.0005 |
| Neopterin (nmol/L) | 7.0 (5.0–8.9) | 7.3 (4.2–10.4) | 0.61 |
| SBP (mmHg) | 130 (120–140) | 130 (120–140) | 0.69 |
| DBP (mmHg) | 80 (80–90) | 80 (80–85) | 0.45 |
| Lipid-lowering treatment (%) | 16 | 43 | 0.0008 |
| Hypertension treatment (%) | 33 | 62 | 0.01 |
| Metformin treatment (%) | 0 | 76 | <0.0001 |
| Menopausal status (% postmenopausal) |
50 | 62 | 0.11 |
| Physical activity (% never or sporadically) |
32 | 35 | 0.72 |
| Alcohol consumption (% never or sporadically) |
94 | 95 | 0.80 |
| Smoker (% current) | 12 | 19 | 0.27 |
| Obesity categories 1/2/3 (%) | 54/18/28 | 45/31/24 | 0.67 |
Means ± SD or medians (25th and 75th percentiles) or %.