Table 5.
The Spearman rank correlation coefficients between Trp, KP metabolites, and metabolic factors according to glycemic status.
| Parameter | NG Correlation Coefficients/T2D Correlation Coefficients | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Trp | Kyn | Kyna | 3HKyn | QA | KTR | KMO | KAT | Kyna/ QA |
Kyna/ 3HKyn |
|
| BMI | 0.29/- | -/- | −0.43 @/- | 0.66 @/- | −0.60 @/- | −0.34 @/- | 0.60 @/- | −0.29/- | 0.41 @/- | −0.63 @/- |
| WC | 0.24/- | -/- | −0.40 @/- | 0.46 @/- | −0.50 @/- | −0.36 @/- | 0.48 @/- | −0.34 @/- | 0.32 @/- | −0.48 @/- |
| Glucose | -/- | -/- | −0.26/- | -/- | -/- | -/- | -/- | -/- | -/- | |
| HOMA-IR | -/- | -/- | -/- | -/0.30 | -/- | -/- | -/- | -/- | -/- | -/−0.28 |
| HDL-C | -/- | -/- | -/- | -/- | -/- | -/- | -/- | -/- | -/- | |
| TG | -/0.29 | -/- | −0.24/- | 0.31 @/- | −033 @/- | -/−0.27 | 0.26/- | -/- | −0.29/- | |
| ALT | -/- | 0.27/ 0.28 |
-/- | -/- | -/- | -/- | -/- | −0.33/ −0.26 |
-/- | -/- |
| GGT | -/- | 0.25/ 0.30 |
-/−0.32 | -/- | -/- | -/- | -/- | −0.35 @/ −0.40 |
-/- | -/- |
| HbA1c | -/- | -/- | -/- | -/- | -/- | -/- | -/- | -/- | -/- | -/- |
| CRP | -/- | -/- | −0.34 @/- | 0.35 @/- | −0.30/- | -/- | 0.34 @/- | -/- | -/- | −0.37 @/- |
| Neopterin | -/- | -/- | -/- | -/0.32 | -/- | -/- | -/- | -/- | -/0.32 | -/−0.26 |
| Creatinine | 0.29/- | -/- | -/- | -/- | −0.27/- | -/- | -/- | -/- | 0.33 @/0.29 | -/- |
| eGFR | −0.26/- | -/- | -/- | -/- | 0.29/- | -/- | -/- | -/- | −0.32 @/ −0.28 |
-/- |
(-) not statistically significant before correction; NG (normoglycemic women); T2D (type 2 diabetes women). @—Statically significant after applying Benjamini–Hochberg correction; text in bold/italic means T2D correlation coefficients.