Table 4.
Physiochemical properties and anticoagulant activities of HfFS and dHf-1~dHf-6.
| Sample | Mw a (kDa) |
Mn (kDa) |
PDI | APTT b (μg/mL) |
PT (μg/mL) |
TT (μg/mL) |
|---|---|---|---|---|---|---|
| HfFS | 443.41 | 136.88 | 3.24 | 46.17 | >128 | >128 |
| dHf-1 | 74.74 | 49.75 | 1.50 | 42.49 | >128 | 74.85 |
| dHf-2 | 27.68 | 21.76 | 1.27 | 82.61 | >128 | >128 |
| dHf-3 | 20.32 | 15.75 | 1.30 | 95.43 | >128 | >128 |
| dHf-4 | 11.50 | 8.88 | 1.30 | >128 | >128 | >128 |
| dHf-5 | 8.26 | 6.86 | 1.20 | >128 | >128 | >128 |
| dHf-6 | 5.99 | 4.80 | 1.25 | >128 | >128 | >128 |
| LMWH | ~4.40 | / | / | 9.60 | / | 1.98 |
a Mw and Mn were determined by HPGPC. b Concentrations required for doubling APTT.