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. 2022 May 27;14(6):1143. doi: 10.3390/pharmaceutics14061143

Figure 4.

Figure 4

Tumor growth inhibition on H460 xenografts by combination of MN58b or RSM-932A/TCD-717 and cisplatin. H460 cells were injected in nude mice, and when tumor volumes reached 0.1 cm3, animals were randomly distributed in groups (n = 8) to start treatments. Mice were treated with the indicated ChoKα and cisplatin (cDPP) either alone or following sequential or concomitant schedules. A significant synergistic effect was observed with the combined therapy in both cases: MN58b (upper) and RSM-932A/TCD-717 (lower).