Table 1.
Dissociation score stratified by OXTR single nucleotide polymorphism (SNP) genotypes (n = 228)a
| Genotype (n) | Dissociation score, mean (s.d.) | Carrier 1 | ||||||
|---|---|---|---|---|---|---|---|---|
| SNP | 1/1 | 1/2 | 2/2 | 1/1 | 1/2 | 2/2 | F; P | t; P |
| rs1042778 | G/G (81) | G/T (120) | T/T (27) | 1.1 (2.4) | 1.0 (2.0) | 0.6 (0.9) | 0.76; 0.467 | 2.15; 0.035 |
| rs237885 | G/G (62) | G/T (117) | T/T (49) | 1.0 (1.9) | 0.9 (1.7) | 1.4 (3.0) | 0.79; 0.457 | −1.05; 0.300 |
| rs237887 | A/A (67) | A/G (120) | G/G (41) | 0.9 (1.5) | 0.9 (1.9) | 1.5 (3.2) | 1.24; 0.296 | −1.27; 0.209 |
| rs237888 | T/T (200) | T/C (27) | C/C (1) | 1.0 (2.1) | 0.8 (1.7) | 4.0b | 1.20; 0.303 | −1.45; 0.150 |
| rs2254298 | G/G (169) | G/A (55) | A/A (4) | 0.9 (1.8)c | 1.0 (1.9) | 4.0 (8.0)c | 0.55; 0.621 | −0.76; 0.501 |
| rs237889 | C/C (87) | C/T (112) | T/T (29) | 1.2 (2.6) | 0.8 (1.7) | 1.1 (1.8) | 0.97; 0.382 | −0.27; 0.785 |
| rs53576 | G/G (111) | G/A (100) | A/A (17) | 1.0 (2.1) | 1.0 (2.1) | 1.1 (2.2) | 0.01; 0.992 | −0.11; 0.911 |
| rs237895 | C/C (88) | C/T (116) | T/T (24) | 1.0 (2.2) | 1.1 (2.2) | 0.3 (0.6) | 9.21; 0.00018 | 4.29; 0.000037 |
| rs237897 | C/C (92) | C/T (112) | T/T (24) | 1.1 (2.3) | 1.1 (2.1) | 0.3 (0.6) | 9.20; 0.00018 | 4.29; 0.000037 |
a.
Results were not corrected for multiple testing, and instead the adjusted P-value of 0.0089 was used at the threshold for significance.
b.
The minor allele homozygote (C/C) of rs237888 occurs only once in the sample; thus, the standard deviation was not available.
c.
Groups with the same letter represent significant differences as tested by one-way analysis of variance with post hoc analysis with Bonferroni correction.