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. 2022 May 30;14(6):1172. doi: 10.3390/pharmaceutics14061172

Figure 3.

Figure 3

To identify that GPR124 is a direct target of miR-138-5p by Microarray and Target Scan. (A) After the identification of miRNA expression signatures by miRNA microarray analysis in endometrial tissue, we searched for putative targets using established miRNA target prediction programs, target Scan 7.2, a web server, in order to explore target genes of miR-138-5p. GPR124 was predicted as a potential target of miR-138-5p by target Scan. We focused on GPR124 because of its established relevance in angiogenesis and atherosclerosis possibly related to embryo implantation. (B) Target Scan analysis forecasted one putative miR-138-5p binding site within the 3′ UTR of GPR124.