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. 2022 Jun 15;27(12):3851. doi: 10.3390/molecules27123851

Table 1.

Mutations in SARS-CoV-2 variants.

Virus Strain NTD Rod
Alpha α
B.1.1.7 (UK)
∆H69 ∆V70
∆Y144
D614G P681H T716I
S982A D1118H
Beta β
B.1.351 (S_Afr)
L18F D80A D215G
∆L242 ∆A243 ∆L244
D614G A701V
n/a
C.1.2 (S_Afr)
P9L C136F ∆Y144 R190S D215G
∆A243 ∆L244
D614G H655Y N679K
T716I T859N
Gamma γ
P.1 (Brazil)
L18F T20N P26S
D138Y R190S
D614G H655Y T1027I V1176F
Delta δ
B.1.617.2 (India)
T19R T95I G142D
∆E156 ∆F157 R158G
D614G P681R D950N
Mu µ
B.621 (Columbia)
T95I +143T Y144S Y145N D614G P681H D950N
Lambda λ
C.37 (Peru)
G75V T76I R246N ∆S247 ∆Y248
∆L249 ∆250
∆P251 ∆G252 ∆D253
D614G T859N
Omicron ο
B.1.1.529 (S_Afr)
A67V ∆H69 ∆V70 T95I G142D
∆V143 ∆Y144 ∆Y145 L212I
+214EPE
D614G H655Y N679K P681H N764K D796Y N856K N954K L981F

Mutation patterns in the NTD and rod-like regions of the SARS-CoV-2 spike protein were obtained from the GISAID database. Deletions (∆) and insertions (+) are indicated.