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Organ biodistribution and intraoperative NIR FLI; (A) “Ex vivo” NIR FLI 6 h after 500 µM injection of RR11 and 23 (MSA14) was performed to assess the compound accumulation in tumors and organs. (B) Representative intraoperative near-infrared (NIR), color and pseudo-colored fluorescent signal merge images of one 23 (MSA14) injected subcutaneously engrafted OVCAR-3 mouse in vivo and ex vivo.
