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. 2022 Jun 18;10(6):972. doi: 10.3390/vaccines10060972

Figure 3.

Figure 3

Figure 3

Figure 3

Concentration of neutralizing antibodies against different variants of the subunit 1 of spike protein (S1) or the receptor-binding domain (RBD) of SARS-CoV-2 in HSCT patients and healthy controls before and after third vaccination. Humoral responses before and after third vaccination against (a) wildtype S1, (b) wildtype RBD, (c) alpha, (d) beta, (e) gamma, (f) E484K, (g) epsilon, (h) kappa, (i) D614G, (j) K417N, and (k) N501Y. D614G is a mutation found in delta and omicron variants, while K417N and N501Y are mutations in the omicron variant. Circles indicate data before the third vaccination (red—HSCT, blue—healthy controls), while triangles indicate data after the third vaccination. Responses were compared by two-tailed Mann–Whitney test (** p < 0.01, *** p < 0.001, **** p <0.0001). Horizontal lines indicate mean values, while error bars indicate the standard deviation.