Table 2. Comparison between pig and baboon as donors.
The advantages and disadvantages of the pig as a potential source of organs and cells for humans, in contrast with those of the baboon in this role, are shown in this table.
Pig | Baboon | |
Availability | Unlimited | Limited |
Breeding potential | Good | Poor |
Period to reproductive maturity | 4–8 months | 3–5 years |
Length of pregnancy | 114 ± 2 days | 173–193 days |
Number of offspring | 5–12 | 1–2 |
Growth | Rapid (adult human size within 6 months) | Slow (9 years to reach maximum size) |
Size of adult organs | Adequate | Inadequate |
Cost of maintenance | Significantly lower | High |
Anatomical similarity to humans | Moderately close | Close |
Physiological similarity to humans | Moderately close | Close |
Relationship of the immune system to humans | Distant | Close |
Knowledge of tissue typing | Considerable (in selected herds) | Limited |
Necessity for blood type compatibility with humans | Probably unimportant | Important |
Experience with genetic engineering | Considerable | None |
Risk of transfer of infection (xenozoonosis) | Low | High |
Availability of specific pathogen-free animals | Yes | Yes |
Public opinion | More in favor | Mixed |