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. 2022 Jun 24;14(6):e26284. doi: 10.7759/cureus.26284

Table 2. Comparison between pig and baboon as donors.

The advantages and disadvantages of the pig as a potential source of organs and cells for humans, in contrast with those of the baboon in this role, are shown in this table.

  Pig Baboon
Availability Unlimited Limited
Breeding potential Good Poor
Period to reproductive maturity 4–8 months 3–5 years
Length of pregnancy 114 ± 2 days 173–193 days
Number of offspring 5–12 1–2
Growth Rapid (adult human size within 6 months) Slow (9 years to reach maximum size)
Size of adult organs Adequate Inadequate
Cost of maintenance Significantly lower High
Anatomical similarity to humans Moderately close Close
Physiological similarity to humans Moderately close Close
Relationship of the immune system to humans Distant Close
Knowledge of tissue typing Considerable (in selected herds) Limited
Necessity for blood type compatibility with humans Probably unimportant Important
Experience with genetic engineering Considerable None
Risk of transfer of infection (xenozoonosis) Low High
Availability of specific pathogen-free animals Yes Yes
Public opinion More in favor Mixed