Table 1.
Association between the expression of CD8, CD20 expression, DDR gene mutations, CNA count and clinical features.
| CD8 (n = 22) | CD20 (n = 22) | DDR Mutation (n = 23) | ||||||||
| Neg/Low | High | p-Value | Neg/Low | High | p-Value | Neg | Pos | p-Value | ||
| (n = 14) | (n = 8) | (n = 14) | (n = 8) | (n = 7) | (n = 16) | |||||
| Age | <62 | 5 | 5 | 0.221 | 4 | 6 | 0.048 | 6 | 4 | 0.012 |
| ≥62 | 9 | 3 | 10 | 2 | 1 | 12 | ||||
| Melanoma subtype | CM | 7 | 3 | 0.917 | 7 | 3 | 0.720 | 2 | 8 | 0.171 |
| HNM | 4 | 3 | 5 | 2 | 4 | 3 | ||||
| UM | 2 | 1 | 1 | 2 | 0 | 4 | ||||
| AM/MM | 1 | 1 | 1 | 1 | 1 | 1 | ||||
| Chemotherapy | Yes | 2 | 4 | 0.096 | 3 | 3 | 0.369 | 1 | 5 | 0.382 |
| No | 12 | 4 | 11 | 5 | 6 | 11 | ||||
| Immunotherapy | 1 ICI | 7 | 4 | 0.670 | 7 | 4 | 0.670 | 5 | 7 | 0.222 |
| 2+ ICI | 7 | 4 | 7 | 4 | 2 | 9 | ||||
| CD20 | High | 3 | 5 | 0.072 | 3 | 5 | 0.510 | |||
| Neg/Low | 11 | 3 | 4 | 10 | ||||||
| DDR mutation | Positive | 9 | 6 | 0.490 | ||||||
| Negative | 5 | 2 | ||||||||
| CNA count | High | 5 | 5 | 0.221 | 5 | 5 | 0.221 | 3 | 8 | 0.556 |
| Low | 9 | 3 | 9 | 3 | 4 | 8 | ||||