Table 2.
MIC and MBC values of ethanolic extract of Romanian propolis and two antibacterial drugs (µg/mL).
| MRSA/MSSA | Ethanolic Extract of Romanian Propolis | Gentamicin (30 µg) | Enrofloxacin (15 µg) | |||
|---|---|---|---|---|---|---|
| MIC (µg/mL) | MBC (µg/mL) | MIC (Sensible ≤ 4; Resistant ≥ 16 µg/mL *) | MIC (Sensible ≤ 0.5; Resistant ≥ 4 µg/mL *) | |||
| Sensible | Resistant | Sensible | Resistant | |||
| Staphylococcus aureus 1—MSSA | 8 | 12 | 2 | - | 0.225 | - |
| Staphylococcus aureus 2—MRSA | 6 | 10 | - | 24 | - | 6 |
| Staphylococcus aureus 3—MSSA | 8 | 10 | - | 18 | 0.125 | - |
| Staphylococcus aureus 4—MSSA | 10 | 14 | 2 | - | 0.75 | - |
| Staphylococcus aureus 5—MRSA | 10 | 12 | - | 18 | 0.5 | - |
| Staphylococcus aureus 6—MRSA | 8 | 10 | - | 22 | 0.125 | - |
| Staphylococcus aureus 7—MSSA | 6 | 8 | 1 | - | 0.75 | - |
| Staphylococcus aureus 8—MSSA | 10 | 12 | 2 | - | 0.225 | - |
| Staphylococcus aureus 9—MSSA | 6 | 8 | 4 | - | - | 4 |
| Staphylococcus aureus 10—MRSA | 6 | 8 | - | 24 | 0.5 | - |
| Staphylococcus aureus 11—MSSA | 8 | 12 | 2 | - | 0.125 | - |
| Staphylococcus aureus 12—MSSA | 8 | 10 | 4 | - | 0.75 | - |
| Staphylococcus aureus 13—MSSA | 10 | 14 | 1 | - | 0.125 | - |
| Staphylococcus aureus 14—MSSA | 6 | 8 | 4 | - | 0.225 | - |
| Staphylococcus aureus 15—MSSA | 6 | 8 | - | 16 | 0.25 | - |
| Staphylococcus aureus 16—MSSA | 8 | 10 | 2 | - | 0.25 | - |
| Staphylococcus aureus 17—MRSA | 10 | 14 | 2 | - | - | 6 |
| Staphylococcus aureus 18—MSSA | 8 | 10 | 4 | - | 0.125 | - |
| Staphylococcus aureus 19—MSSA | 8 | 10 | - | 18 | 0.225 | - |
| Staphylococcus aureus 21—MRSA | 6 | 8 | - | 24 | - | 8 |
| Staphylococcus aureus 22—MSSA | 6 | 6 | 2 | - | 0.5 | - |
| Staphylococcus aureus 23—MSSA | 8 | 10 | 2 | - | 0.125 | - |
| Staphylococcus aureus 24—MRSA | 10 | 14 | 4 | - | 0.25 | - |
| Staphylococcus aureus 25—MRSA | 10 | 12 | 4 | - | - | 6 |
| Staphylococcus aureus 26—MSSA | 8 | 10 | 1 | - | 0.125 | - |
| Staphylococcus aureus 27—MSSA | 6 | 8 | 2 | - | 0.225 | - |
| Staphylococcus aureus 28—MSSA | 6 | 6 | - | 18 | 0.5 | - |
| Staphylococcus aureus 29—MSSA | 10 | 12 | 1 | - | 0.25 | - |
| Staphylococcus aureus 30—MRSA | 8 | 8 | 4 | - | - | 8 |
| Staphylococcus aureus 31—MSSA | 10 | 12 | 2 | - | - | 6 |
| Staphylococcus aureus 32—MRSA | 6 | 8 | 4 | - | 0.125 | - |
| Staphylococcus aureus 33—MSSA | 6 | 8 | - | 22 | 0.25 | - |
| Staphylococcus aureus 34—MSSA | 8 | 10 | 1 | - | 0.5 | - |
| Staphylococcus aureus 35—MRSA | 8 | 8 | 2 | - | 0.125 | - |
| Staphylococcus aureus 36—MSSA | 10 | 12 | - | 16 | 0.125 | - |
| Staphylococcus aureus 37—MSSA | 10 | 14 | 2 | - | 0.25 | - |
| Staphylococcus aureus 38—MRSA | 8 | 10 | 4 | - | 0.225 | - |
| Staphylococcus aureus ATCC 25923—MSSA | 8 | 10 | 1 | - | 0.225 | - |
| Staphylococcus aureus ATCC 43300—MRSA | 8 | 10 | 2 | - | 0.225 | - |
| Total (Mean + STDEV.P) | 9.483 | 12.344 | 3.339 | 16 | 0.5 | 8 |
* CLSI: Performance standard for antimicrobial disk susceptibility test, 13th ed. CLSI M02 Wayne, PA, Clinical and Laboratory Standard Institute, 2018.