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. 2022 Jun 9;27(12):3714. doi: 10.3390/molecules27123714

Table 1.

The IC50 values of tanshinones to U−2 OS cells, Hela cells, and NRK−49F cells.

IC50 (µM) DS−1 DS−2 DS−3 DS−4 DS−5
U−2 OS cells (24 h) 3.83 ± 0.49 47.84 ± 4.96 17.75 ± 1.03 22.06 ± 1.31 25.40 ± 1.43
(48 h) 1.99 ± 0.37 25.60 ± 0.81 4.54 ± 1.00 5.89 ± 0.40 5.91 ± 1.08
HeLa cells (24 h) 15.48 ± 0.98 52.07 ± 3.20 20.92 ± 2.81 25.03 ± 2.03 32.09 ± 1.94
NRK−49F cells (24 h) 25.00 ± 1.98 35.39 ± 3.25 107.60 ± 28.85 31.84 ± 1.59 / a

a no significant cytotoxicity.