Figure 1.
Comparison of (a) MPA–AUC0–12h; (b) dose-adjusted MPA–AUC0–12h; (c) MPA–CL/F, between Group 1 (MMF + CsA group) and Group 2 (MMF + TAC group) and corresponding p-value of the Mann–Whitney test. Median values with the corresponding 95% confidence intervals (bars). Dots represent the outliers. In (a), the interval between the dotted lines represents the therapeutic range (30–60 mg·h/L). Nomenclature: AUC0–12h—area under the 12 h concentration–time curve; Cl/F—apparent clearance; CsA—cyclosporine; MPA—mycophenolic acid; MMF—mycophenolate mofetil; TAC—tacrolimus.
