| CARD | caspase activation and recruitment domain |
| CCL2 | chemokine ligand 2 |
| 3CLpro | protease 3C-like |
| DMV | double-membrane vesicle |
| dsRNA | double-stranded RNA |
| E | envelope |
| FDA | United States Food and Drug Administration |
| IFN | interferon |
| IFNAR | IFN-α receptor |
| IL | interleukin |
| IFN-LR1 | IFN-l receptor 1 |
| IKKα/ß | inhibitor of nuclear factor kappa-B kinase |
| IRF | IFN-regulatory factor |
| ISG | IFN-stimulated gene |
| ISRE | IFN-stimulated response element |
| ISGF | IFN-stimulated gene factor |
| JAK | Janus-associated kinase |
| KPNA2 | importin karyopherin α 2 |
| M | membrane |
| MAVS | mitochondrial-associated viral signaling protein |
| MDA5 | melanoma differentiation-associated protein 5 |
| N | nucleocapsid |
| NEMO | NF-κB essential modulator |
| NF-kB | nuclear factor kB |
| NPC | nuclear pore complex |
| NSP | nonstructural protein |
| ORF | open reading frame |
| PAMP | pathogen-associated molecular patterns |
| PLpro | papain-like protease |
| PRR | pattern-recognition receptors |
| RIG-I | retinoic acid-inducible gene I protein |
| RdRp | RNA-dependent RNA polymerase |
| RT-qPCR | reverse transcription-quantitative PCR |
| SARS-CoV-2 | severe acute respiratory syndrome coronavirus 2 |
| sgRNA | subgenomic RNA |
| S | spike |
| SREBP1 | sterol regulatory element-binding protein 1 |
| SRP | signal recognition particle |
| STAT | transducer and activator of transcription |
| TBK1 | TANK-binding kinase 1 |
| TLR | Toll-like receptor |
| TNF | tumor necrosis factor |
| TRAF | TNF receptor-associated factor |
| TYK | tyrosine kinase |
| WHO | World Health Organization |