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. 2022 Jun 8;14(6):1247. doi: 10.3390/v14061247
CARD caspase activation and recruitment domain
CCL2 chemokine ligand 2
3CLpro protease 3C-like
DMV double-membrane vesicle
dsRNA double-stranded RNA
E envelope
FDA United States Food and Drug Administration
IFN interferon
IFNAR IFN-α receptor
IL interleukin
IFN-LR1 IFN-l receptor 1
IKKα/ß inhibitor of nuclear factor kappa-B kinase
IRF IFN-regulatory factor
ISG IFN-stimulated gene
ISRE IFN-stimulated response element
ISGF IFN-stimulated gene factor
JAK Janus-associated kinase
KPNA2 importin karyopherin α 2
M membrane
MAVS mitochondrial-associated viral signaling protein
MDA5 melanoma differentiation-associated protein 5
N nucleocapsid
NEMO NF-κB essential modulator
NF-kB nuclear factor kB
NPC nuclear pore complex
NSP nonstructural protein
ORF open reading frame
PAMP pathogen-associated molecular patterns
PLpro papain-like protease
PRR pattern-recognition receptors
RIG-I retinoic acid-inducible gene I protein
RdRp RNA-dependent RNA polymerase
RT-qPCR reverse transcription-quantitative PCR
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
sgRNA subgenomic RNA
S spike
SREBP1 sterol regulatory element-binding protein 1
SRP signal recognition particle
STAT transducer and activator of transcription
TBK1 TANK-binding kinase 1
TLR Toll-like receptor
TNF tumor necrosis factor
TRAF TNF receptor-associated factor
TYK tyrosine kinase
WHO World Health Organization