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. 2021 Dec 21;12:773896. doi: 10.3389/fimmu.2021.773896

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Copyright © 2021 Liu, Chen, Qiu, Chen and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationships between different B cell subsets and clinical data from all the study subjects. (A) Correlations between IL-10⁺ Bregs and FBG. (B) Correlations between Tim-1⁺ Bregs and FBG. (C) Correlations between IL-10⁺ Bregs and FCP. (D) Correlations between Tim-1⁺ Bregs and FCP. (E) Correlations between IL-10⁺ Bregs and HbA1c. (F) Correlations between IL-10⁺ Bregs and Tim-1⁺ Bregs in T1D. Each point represents an individual patient with T1D, T2D and healthy controls. ^* P < 0.05. ^*** P < 0.001.