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. 2021 Dec 21;12:777670. doi: 10.3389/fphar.2021.777670

FIGURE 2.

FIGURE 2

ZWT protected renal function and structural changes in chronic glomerulonephritis (CGN) model rats. (A,B) The levels of blood urea nitrogen (BUN) and serum creatinine (Scr). (C) Representative images of PAS-stained renal sections (×400 magnification; scale bar = 20 μm). (D) Representative images of renal tissue ultrastructure by transmission electron microscopy (×5,000 magnification; scale bar = 5 μm). Red arrows indicate foot process. Green arrows indicate glomerular basement membrane (GBM). (E,F) Quantitative analysis of foot process width and GBM thickness. Data are represented as mean ± SD (n = 8). ## p < 0.01 versus normal group, *p < 0.05 and **p < 0.01 versus model group. ZWT ameliorated mitochondrial dysfunction in CGN model rats.