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. Author manuscript; available in PMC: 2022 Jun 24.
Published in final edited form as: Free Radic Biol Med. 2021 Aug 31;175:95–107. doi: 10.1016/j.freeradbiomed.2021.08.238

Figure 5: Right ventricular functional analysis in hemopexin treated and untreated SCD mice experiencing progressive cardiopulmonary vascular disease.

Figure 5:

(A) Representative tracings of pressure volume (PV) loops during an occlusion (B) shows the corresponding schematics of the pressure volume relationships for hemopexin treated and untreated SCD mice. (C-J) Right ventricular stiffness, contractility, stroke volume, cardiac output, heart rate, preload and ejection fraction. Data is represented as means ± standard error of measurement. Inset graphs show low and high dose Hpx treated mice combined into one group. RVSP- right ventricular pressures; Ea-Afterload; EDPVR-end diastolic pressure volume relationship; ESPVR- end systolic pressure volume relationship. *p<0.05, **p<0.005