Figure 7: Microscopic examination of lung and right ventricle tissues in hemopexin treated and untreated SCD mice.
(A) Histopathology of lung tissue . Top row- Perls iron staining; Middle rows show 4HNE staining for lipid peroxidation; Bottom row- Trichrome staining as a marker for fibrosis; (B) Histopathology of right ventricle tissue Top row- Perls iron staining; Middle rows show 4HNE staining for lipid peroxidation (C) Confocal microscopy images of showing the distribution of hemoglobin and hemopexin extravasation into cardiac tissue 30 min after administration.
