Table 3.

Serum and salivary analytes at three timepoints.

	Visit 1	Visit 2	Visit 3
	(saliva, n = 815)	(saliva, n = 42)	(saliva, n = 352; serum, n = 332)
CRP Mean (SD)
Saliva (pg/mL)	2.22 (0.71)	2.57 (0.52)	2.56 (0.56)
Serum (pg/mL)	··	··	5.99 (0.74)
Insulin Mean (SD)
Saliva (pg/mL)	1.74 (0.62)	2.48 (0.41)	2.46 (0.36)
Serum (pg/mL)	··	··	2.89 (0.30)
Adiponectin Mean (SD)
Saliva (pg/mL)	3.57 (0.41)	3.84 (0.42)	3.72 (0.39)
Serum (pg/mL)	··	··	6.90 (0.29)
Leptin Mean (SD)
Saliva (pg/mL)	0.39 (1.23)	2.21 (0.15)	2.24 (0.25)
Serum (pg/mL)	··	··	4.14 (0.51)
IL-6 Mean (SD)
Saliva (pg/mL)	0.88 (0.49)	0.94 (0.60)	0.70 (0.41)
Serum (pg/mL)	··	··	0.04 (0.38)
IL-8 Mean (SD)
Saliva (pg/mL)	2.74 (0.47)	3.10 (0.42)	2.67 (0.34)
Serum (pg/mL)	··	··	0.76 (0.23)
IL-10 Mean (SD)
Saliva (pg/mL)	0.65 (0.42)	0.20 (0.31)	0.38 (0.33)
Serum (pg/mL)	··	··	0.17 (0.40)
MCP-1 Mean (SD)
Saliva (pg/mL)	2.42 (0.29)	2.56 (0.26)	2.48 (0.33)
Serum (pg/mL)	··	··	2.44 (0.23)
VEGF Mean (SD)
Saliva (pg/mL)	2.47 (0.30)	3.07 (0.21)	2.78 (0.28)
Serum (pg/mL)	··	··	1.82 (0.33)

The biomarkers data were reported in the log form and only those that were detectable were included.

CRP, C-Reactive Protein; SD, Standard Deviation; IL-6, Interleukin-6; IL-8, Interleukin-8; IL-10, Interleukin-10; MCP-1, Monocyte Chemoattractant Protein-1; VEGF, Vascular Endothelial Growth Factor. ··, N/A.